Cambridge IGCSE0610

Cell structure

Biology 0610 Chapter Notes

What this chapter covers

Cell structureSize of specimens
ShareWhatsAppPost
Cell structure notes

Unable to load PDF

The notes viewer could not load. Please refresh the page.

Read online free. Download a watermarked copy with a free account.

Read the notes

The full Cell structure notes as text: skim, search, and jump between subtopics.

~12 min read

1. Introduction to Cells

All living organisms, from the smallest bacterium to the largest whale, are made up of fundamental units called cells. A cell is the smallest unit of life that can carry out all the processes necessary for living. Most cells are too small to be seen with the naked eye, so we use microscopes to study them. The study of cells is the foundation of biology, as everything an organism does is ultimately the result of the activities of its cells.

Key term

Cell: The basic structural, functional, and biological unit of all known living organisms.

Fun fact

Your body is made of an estimated 37 trillion cells, and they come in about 200 different types!

Worked example 13 marks

The diagram shows a typical animal cell. Identify the structures labelled A, B, and C.

  1. 1

    Structure A is the central, often spherical body that contains the genetic material. This is the nucleus.

  2. 2

    Structure B is the jelly-like substance that fills the cell and surrounds the nucleus. This is the cytoplasm.

  3. 3

    Structure C is the outer boundary of the animal cell that controls what enters and leaves. This is the cell membrane.

Recap

  • All living things are composed of one or more cells.
  • The cell is the most basic unit of life.
  • Microscopes are essential tools for observing cells.
  • Cells contain smaller components called organelles that perform specific jobs.

Quick check

  1. What instrument is required to view most cells?1 mark
  2. State the three main parts of a basic animal cell visible under a light microscope.3 marks

2. Comparing Animal and Plant Cells

While all eukaryotic cells share some common features, there are key differences between animal and plant cells, largely due to their different ways of life. Plants are stationary and make their own food (autotrophs), while animals typically move and consume other organisms (heterotrophs). These differences are reflected in their cell structure.

Common features:

  • Nucleus: Controls cell activities and contains genetic material.
  • Cytoplasm: Jelly-like substance where chemical reactions occur.
  • Cell membrane: Controls the movement of substances into and out of the cell.
  • Mitochondria: Site of aerobic respiration to release energy.
  • Ribosomes: Site of protein synthesis.

Features unique to plants (and some other organisms):

  • Cellulose Cell Wall: A rigid outer layer that provides structural support and prevents the cell from bursting.
  • Large Permanent Vacuole: Contains cell sap (a solution of sugars, salts, and amino acids) and helps maintain the cell's shape and turgidity.
  • Chloroplasts: Contain the green pigment chlorophyll and are the site of photosynthesis.

Key term

Cellulose Cell Wall: A rigid layer made of cellulose that is found outside the cell membrane of plant cells, providing structural support and protection.

Examiner insight

Examiners award marks for clearly stating which structures are present in plant cells but absent in animal cells. Be specific, for example, 'cellulose cell wall' is better than just 'cell wall'.

Common pitfall

Stating that animal cells have no vacuole at all; they can have small, temporary vacuoles, which are structurally and functionally different from the large, permanent vacuole in plants.

Worked example 13 marks

List three structural differences between a liver cell (an animal cell) and a palisade cell (a plant cell).

  1. 1

    A palisade cell has a cellulose cell wall, whereas a liver cell does not.

  2. 2

    A palisade cell contains chloroplasts for photosynthesis, whereas a liver cell does not.

  3. 3

    A palisade cell has a large, central, permanent vacuole, whereas a liver cell has only small, temporary vacuoles, if any.

Recap

  • Animal and plant cells share a nucleus, cytoplasm, cell membrane, and mitochondria.
  • Plant cells have three additional structures: a cellulose cell wall, chloroplasts, and a large permanent vacuole.
  • The cell wall provides rigid support to plant cells.
  • Chloroplasts are the site of photosynthesis in plant cells.
  • The large vacuole helps maintain turgor pressure against the cell wall.

Quick check

  1. Name two structures found in a palisade cell but not in a liver cell.2 marks

3. Cell Organelles and their Functions

Organelles are 'little organs' within the cell, each performing a specific job to keep the cell alive and functioning correctly. This is known as the division of labour within the cell.

  • Nucleus: Often called the 'control centre'. It contains the cell's genetic material (DNA) in the form of chromosomes. It controls all the activities of the cell, such as growth and cell division.
  • Cytoplasm: A jelly-like substance that fills the cell. It's where most of the cell's metabolic chemical reactions take place. Organelles are suspended within it.
  • Cell Membrane: A partially permeable barrier that surrounds the cell. It controls which substances can enter and leave the cell, such as oxygen, nutrients, and waste products.
  • Mitochondria (singular: mitochondrion): The 'powerhouses' of the cell. This is where aerobic respiration occurs, a process that releases energy from glucose for the cell to use.
  • Ribosomes: Tiny structures, either free in the cytoplasm or attached to the endoplasmic reticulum. They are responsible for making proteins (protein synthesis).
  • Cell Wall (Plants only): A fully permeable outer layer made of cellulose. It provides strength, support, and protection, preventing the plant cell from bursting when it takes in too much water.
  • Chloroplasts (Plants only): Disc-shaped organelles containing chlorophyll. They are the site of photosynthesis, where light energy is used to make food (glucose).
  • Large Permanent Vacuole (Plants only): A large, membrane-bound sac filled with cell sap. It helps to support the cell by pushing the cytoplasm against the cell wall, maintaining turgor pressure.

Key term

Mitochondrion: An organelle found in large numbers in most cells, in which the biochemical processes of aerobic respiration and energy production occur.

Fun fact

Mitochondria have their own DNA, separate from the nucleus, supporting the theory that they were once independent bacteria that were engulfed by a larger cell.

Worked example 15 marks

The table below describes some cell structures. Match each structure with its description. Write the letter and number to show your answer, for example, a-4.

StructureDescription
a Cell membrane1 Structures which contain chlorophyll
b Nucleus2 Main site of protein synthesis
c Chloroplasts3 Sites of aerobic respiration
d Mitochondria4 Controls entry and exit of substances
e Ribosomes5 Carries genetic information and controls cell activities
  1. 1

    a - 4: The cell membrane controls the entry and exit of substances.

  2. 2

    b - 5: The nucleus carries genetic information and controls cell activities.

  3. 3

    c - 1: Chloroplasts are the structures which contain chlorophyll.

  4. 4

    d - 3: Mitochondria are the sites of aerobic respiration.

  5. 5

    e - 2: Ribosomes are the main site of protein synthesis.

Recap

  • The nucleus controls the cell's activities.
  • The cell membrane controls what enters and leaves the cell.
  • Mitochondria are the site of aerobic respiration, releasing energy.
  • Chloroplasts are the site of photosynthesis in plant cells.
  • Ribosomes synthesise proteins.
  • The cell wall provides structural support to plant cells.

Quick check

  1. Which organelle is the site of aerobic respiration?1 mark
  2. What is the function of the cell membrane?1 mark

4. Microscopy and Magnification

To calculate the size of microscopic objects, we use the relationship between the size of the image (what we see through the microscope or in a diagram), the actual size of the object, and the magnification. This can be remembered with the formula triangle 'IAM'.

Image Size (I) = Actual Size (A) × Magnification (M)

It is crucial to work in consistent units. In biology, we often use millimetres (mm) and micrometres (µm). Key conversion: 1 mm = 1000 µm To convert mm to µm, you multiply by 1000. To convert µm to mm, you divide by 1000.

Magnification = Image size / Actual size

Key term

Magnification: The number of times larger an image is compared to the actual size of the object.

Examiner insight

Show your working clearly, including the formula and any unit conversions. Marks are often awarded for correct intermediate steps, even if the final answer is wrong.

Common pitfall

Forgetting to convert units before applying the formula. For example, dividing an image size in mm by an actual size in µm will give an incorrect magnification.

Worked example 13 marks

A student draws a diagram of a cell. The diagram is 60 mm long. The actual length of the cell is 20 µm. Calculate the magnification of the diagram.

  1. 1

    Step 1: Ensure units are consistent. Convert the image size from mm to µm. Image size = 60 mm × 1000 = 60,000 µm.

  2. 2

    Step 2: State the formula. Magnification = Image size / Actual size.

  3. 3

    Step 3: Substitute the values into the formula. Magnification = 60,000 µm / 20 µm.

  4. 4

    Step 4: Calculate the final answer. Magnification = x3000.

Worked example 23 marks

The photograph of a palisade cell is magnified 500 times. On the photograph, the cell measures 75 mm in length. Calculate the actual length of the palisade cell in µm.

  1. 1

    Step 1: Rearrange the formula to find Actual size. Actual size = Image size / Magnification.

  2. 2

    Step 2: Ensure units are consistent for the final answer. The image size is 75 mm. Let's convert this to µm first. Image size = 75 mm x 1000 = 75,000 µm.

  3. 3

    Step 3: Substitute the values into the formula. Actual size = 75,000 µm / 500.

  4. 4

    Step 4: Calculate the final answer. Actual size = 150 µm.

Recap

  • Magnification = Image size / Actual size.
  • Always convert measurements to the same unit before calculating.
  • The standard unit for cell measurements is the micrometre (µm).
  • 1 millimetre (mm) is equal to 1000 micrometres (µm).

Quick check

  1. If an image is magnified x400 and appears 80 mm long, what is the actual size of the object in µm?2 marks

5. Specialised Cells

In multicellular organisms, cells become specialised to perform a particular function. This process is called differentiation. The cell's structure is adapted to make it efficient at its job. For example:

  • Root Hair Cells (Plants): Found on the surface of plant roots. They have a long, thin extension which dramatically increases the surface area for efficient absorption of water and mineral ions from the soil.
  • Red Blood Cells (Animals): Transport oxygen. They have a biconcave disc shape to increase the surface area to volume ratio for diffusion. They contain haemoglobin to bind with oxygen and have no nucleus to maximise space for haemoglobin.
  • Palisade Mesophyll Cells (Plants): The main site of photosynthesis. They are packed with chloroplasts, are rectangular and arranged in columns at the top of the leaf to maximise light absorption.
  • Sperm Cells (Animals): Carry male genetic material to the egg. They have a tail (flagellum) for swimming and mitochondria to provide energy for movement. The acrosome in the head contains enzymes to digest the egg membrane.

Key term

Differentiation: The process where a cell develops new sub-cellular structures to become specialised for a particular function.

Examiner insight

Examiners look for clear, explicit links between a feature and its function. Use connecting phrases like 'this allows...', 'which means that...', or 'in order to...'.

Common pitfall

Simply listing features of a specialised cell without explaining how each feature helps it perform its specific function. You must always link structure to function.

Worked example 13 marks

Explain how a red blood cell is adapted to its function of transporting oxygen.

  1. 1

    Feature 1: It has a biconcave shape. Explanation: This increases the surface area to volume ratio, allowing for faster diffusion of oxygen into and out of the cell.

  2. 2

    Feature 2: It contains haemoglobin. Explanation: This is a red pigment that binds reversibly with oxygen in the lungs to transport it to the body tissues.

  3. 3

    Feature 3: It has no nucleus. Explanation: This maximises the internal space of the cell, allowing it to carry more haemoglobin and therefore more oxygen.

Recap

  • Specialised cells have specific adaptations to carry out their function efficiently.
  • A root hair cell has a large surface area for absorption.
  • A red blood cell has no nucleus to maximise space for oxygen-carrying haemoglobin.
  • A palisade cell is packed with chloroplasts for photosynthesis.
  • Adaptation questions require you to link a structural feature to its functional advantage.

Quick check

  1. State one adaptation of a plant root hair cell and explain how it helps its function.2 marks

6. Levels of Biological Organisation

In complex multicellular organisms, there is a division of labour. Cells are organised into a hierarchy of structures to perform tasks efficiently.

  1. Cells: The basic building blocks (e.g., a muscle cell).
  2. Tissues: A group of similar cells working together to perform a specific function (e.g., muscle tissue, which contracts).
  3. Organs: A structure made of different tissues working together to perform a specific, complex function (e.g., the heart, made of muscle, nervous and connective tissues, pumps blood).
  4. Organ Systems: A group of organs working together to perform a major function in the body (e.g., the circulatory system, including the heart, arteries and veins, transports substances around the body).
  5. Organism: The entire living being, made up of many organ systems working together.

An example in a plant: Palisade cell → Palisade mesophyll tissue → Leaf (organ) → Shoot system → Plant (organism).

Key term

Tissue: A group of similar cells from the same origin that together carry out a specific function.

Fun fact

The largest organ in the human body is the skin, which is part of the integumentary system. The largest organ inside the body is the liver.

Worked example 12 marks

Arrange these biological terms in order of size, from the smallest to the largest: organ, cell, organism, tissue, organ system.

  1. 1

    The smallest unit is the cell.

  2. 2

    A group of cells forms a tissue.

  3. 3

    A group of tissues forms an organ.

  4. 4

    A group of organs forms an organ system.

  5. 5

    All the organ systems together form the organism.

  6. 6

    Final order: Cell, Tissue, Organ, Organ System, Organism.

Recap

  • The levels of organisation are: Cells → Tissues → Organs → Organ Systems → Organism.
  • A tissue is a group of similar cells with a shared function.
  • An organ is a collection of different tissues working together.
  • An organ system is a group of organs that cooperate to perform a major bodily function.

Quick check

  1. Define the term 'organ'.1 mark
  2. Place the following in order of increasing complexity: stomach, human, epithelial tissue, digestive system.2 marks

End-of-chapter exercise

Test yourself on the whole chapter. Work through these before moving on.

  1. Copy and complete the table by placing a tick (✓) if the structure is present and a cross (✗) if it is not. | Structure | Liver cell | Palisade cell | | :--- | :--- | :--- | | Cell surface membrane | | | | Chloroplasts | | | | Cellulose cell wall | | |3 marks
  2. Define the term 'organ system' and give one named example from a plant.2 marks
  3. A micrograph shows a cell magnified by a factor of x800. The length of the cell in the micrograph is 120 mm. Calculate the actual length of the cell in micrometres (µm). Show your working.3 marks
  4. Describe the functions of the following organelles: a) nucleus, b) mitochondria, c) ribosomes.3 marks
  5. Explain how the structure of a palisade mesophyll cell is adapted for its function of photosynthesis.4 marks
  6. State three structural differences between a bacterium and a typical animal cell.3 marks
  7. The diagram shows a sperm cell. Explain how the structures labelled A (tail/flagellum) and B (mid-piece packed with mitochondria) help the cell to carry out its function.4 marks
  8. Explain the concept of 'division of labour' in a multicellular organism. Refer to cells, tissues, and organs in your answer, using the human respiratory system as an example.5 marks
  9. A student looks at a cell from a plant root under a microscope. List two structures they would see that are not present in a cell from a human cheek.2 marks
  10. A student observes a cell under a microscope. It has a cell wall, cytoplasm, and a nucleus, but no visible chloroplasts. The student concludes it must be a plant root cell. Evaluate this conclusion, explaining why it is likely correct and what other type of organism this cell could potentially belong to.4 marks

Go deeper

Practise and revise with member-only material for this chapter.

Free notes are just the start.

Unlock every Workbook and Chapter at a Glance, and generate your own worksheets and predicted papers.

Explore plans

Related chapters